Carlton coach Michael Voss has played down any concern surrounding key forward Charlie Curnow's ankle injury, however the Blues will be forced into at least one change for their trip to Adelaide for next week's Gather Round clash with Fremantle.

Curnow did not see out Friday's 56-point win over North Melbourne after hurting his ankle with several minutes left in the game, causing some angst among Blues fans for their two-time Coleman Medal winner.

The Blues spearhead was able to make his way off the field under the held of club trainers and would gain further treatment on the interchange, remaining on the sideline until the final siren.

With Curnow's history of significant setbacks, the Blues were able to take a cautious approach with their star forward and decided to "put the cue in the rack" with the game all but over.

"Yeah he's OK," Voss said post-game.

"With about fight minutes to go he wasn't fighting me too hard, he was happy to put the cue in the rack with a couple of minutes to go.

"He did actually roll his ankle and obviously came off the ground limping, but there were four minutes left on the clock so we thought we'd park it."

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Carlton won't have defender Caleb Marchbank for their Round 4 interstate venture after the backman suffered a concussion in a marking contest during the second half.

His absence will likely open the door for one of Lewis Young or Brodie Kemp, who were both omitted from Voss' side for Good Friday.

Curnow and partner in crime Harry McKay were again near-unstoppable as a forward combination against an undersized North Melbourne outfit, combining for nine goals in a dominant attacking display.

McKay has started the season as arguably the Blues' best player, shaking off any goalkicking concerns to start the year with 11 goals and just the two behinds across his trio of appearances.

Speaking on the 2021 Coleman Medal winner, Voss said McKay is "as confident as I've seen".

"He went through a journey last year, like all of us. He found some challenges he had to work his way through," Voss said.

"It's amazing when you take the time to work through that. It doesn't always fall how you want it to at that particular time. He's been able to use all of that and now putting in and refining his game.

"He's as confident as I've seen him since I've been here. If anything, he's finally got some reward for the great pre-seasons that he's had. To see that transfer, now into the early part of the season, that's been particularly impressive."

Friday's win sees the Blues head to Gather Round undefeated, with a mouth-watering clash against fellow 3-0 side Fremantle to come at Adelaide Oval on Saturday, April 6.