The Eagles say they are "unlikely" to trade Pick 1, but are more than willing to listen to offers if they come.
West Coast will have a strong hand in next month's National Draft, currently holding Picks 1, 16, 22, 23, 37 and 57, and will acquire Pick 2 as Oscar Allen compensation.
Their hand was enhanced by the AFL's assistance package, which netted the Western Australian club with Pick 19 (now 22) and four extra rookie list spots.
However, there's a minor hold-up regarding the Brandon Starcevich move, which is heading towards a trade that will land the Brisbane premiership defender.
But that won't stop the Eagles from considering a major draft shake-up.
"At this stage, we'd be unlikely to trade pick one, but you never know," Eagles list boss Matt Clarke said, according to AFL Media.
"If there's some clubs that want to move up and might have multiple picks, we'll have a look at it.
"Our recruiting team will do their (draft) ratings again this week, and we'll see what that looks like."
The Eagles are resolute that the Allen and Starcevich deals are separate and will act accordingly in their dealings with the Lions.
"We respect Oscar's right to move under free agency, but the two deals, in our opinion, are completely independent," Clarke said.
"It's up to Brisbane when they want to lodge a free agency deal for Oscar."
Clarke also declared that Pick 16 is too high a value for Starcevich.
The free agency deadline is Friday, and trading ends the following Wednesday.
