The second-year Demon booted three goals from 31 possessions against GWS in Round 15 of the VFL to strengthen his case for a debut, with the club confirming on Wednesday night that the 20-year-old will lace up the boots to face the Saints.
Woewodin joined Melbourne as the 65th and last selection in the 2021 National Draft, moving from East Fremantle as a father-son selection to pull on the red and blue and follow in his Dad's footsteps.
Shane Woewodin played 138 games for Melbourne between 1997-2002, winning the Brownlow Medal in 2000 as the Demons booked themselves a place in the grand final.
After being named as an emergency in recent weeks, the junior Woewodin will now be rewarded for his impressive form with Casey with an AFL debut.
Woewodin is able to play through midfield and in the forward line as a flank player, standing at 182cm, and will wear the No.40 jumper. He'll become the Demons' fourth debutant of 2023, following Judd McVee, Jacob van Rooyen and Bailey Laurie.
Melbourne will make at least one forced change for their clash with St Kilda after forward Bayley Fritsch suffered a foot injury in his side's defeat to GWS last Sunday.
Midfielder Clayton Oliver looms as a short chance to make his return from a hamstring injury in Round 17 following a midweek training stint that was ended prematurely.
Melbourne will confirm their squad to face the Saints on Thursday evening at 6:20pm (AEST) ahead of Saturday's clash at Marvel Stadium.