Durdin suffered a deep cut to his pinky finger, which will leave out of full training for around two months.
The injury dents Durdin’s chances of a breakout season.
The 22-year-old has managed nine games since being drafted in 2014, but has failed to make himself part of the best 22 consistently.
The injury comes at a frustrating time for North Melbourne too.
The Kangaroos will now have four defenders unavailable for round one, with Durdin, Majak Daw (hip/pelvis), Robbie Tarrant (A/C joint) and Scott Thompson (suspension) all set to miss although the side are hopeful that Tarrant will be fit.