Carlton will be without midfielder Matt Kennedy for a majority of the remaining rounds of the season after suffering a high-grade medial knee injury in Sunday's win over Fremantle.

Kennedy was unable to finish the match due to the ailment and underwent scans in the wake of the weekend to learn of the full extent of the setback.

While avoiding a feared ACL injury, Kennedy has managed to avoid a season-ending setback, but is no certainty of returning in 2023.

The setbac will place Kennedy into a period of rehabilitation, with a return potentially coming before the end of the home and away season, meaning Kennedy is facing close to six weeks on the sidelines.

Elsewhere, defender Mitch McGovern (cork) and tall Tom De Koning (knee) will need to prove their fitness in the coming days to be cleared to face Port Adelaide on Saturday.

McGovern suffered the knock against the Dockers but was able to return to play, seeing out the match.

De Koning is in the frame to return from a knee injury that has kept him out of action the past two weeks, while forward Corey Durdin is also in the frame for selection after overcoming a knee injury.

Ruckman Marc Pittonet will require further assessment and is unlikely to be cleared to play this week.

After suffering a concussion in the VFL, fringe midfielder Paddy Dow is expected to be available for selection this week.

Carlton host Port Adelaide at Marvel Stadium at 4:35pm (AEST) on Saturday.