As reported by The Age's Peter Ryan, Francis will subsequently miss the Bombers' clash with the Hawks on Sunday in Launceston, and was expected to return to his home state of South Australia for a short break before hopefully returning at the end of next week.
The rising backman has previously required time away from football to aid his mental health, taking breaks from the game in the past.
Francis has been limited to 10 games so far this season due to injuries, missing Essendon's Round 11 win over West Coast in Perth after suffering from illness and being a late out for the match.
An injury-impacted 2020 season placed Francis on the sidelines for a majority of the campaign as he managed just the eight games in the red and black.
The Bombers are currently without Andrew McGrath (knee), Michael Hurley (hip), Jye Caldwell (hamstring), Dylan Shiel (knee) due to injuries, but are tipped to welcome the returns of Sam Draper, Devon Smith and Peter Wright for Sunday's clash.