Richmond midfielder Jacob Hopper will be out for at least the next fortnight with a mild hamstring strain, scans confirmed.

Hopper, who was arguably the Tigers' best in Wednesday night's Anzac Day Eve loss to Melbourne, was seen clutching his left leg during the third term in a game where he returned from injury.

The former Giant played his second game of the season after overcoming a knee injury, which was heavily strapped on Wednesday.

Footage revealed Hopper's frustration with the new injury, to which he explained the following day.

"Obviously angry that it happened. To cop a bit of another injury was just frustrating," Hopper said at Punt Road on Thursday.

"Hopefully (I) don't kick too many more bottles, because I ... regretted it as soon as I did, because someone could have copped a bottle to the head.

"I'm trying to apologise to everyone on the bench, but obviously pretty frustrating at the time.

"I think a bit of in denial at that stage (when I played on) ... as we were well and truly in the game as well. Then I felt like it probably wasn't the smartest decision (to play on)," he said.

After the match in Richmond coach Adem Yze's offered a strange reason as to why Hopper may have gone down injured.

"I think it's one of the first games that he's played with tape on his knee, so we originally thought it was something to do with the tape and whether the tape was too tight and things like that," Yze said post-game.

"And he hasn't hurt his hammy before, so he tried to stay out there and run it out.

"I think the fact that he had a taped knee made it a little bit uncomfortable."

Since joining Punt Road ahead of the 2023 season, Hopper has featured in 19 games in the yellow and black, and will miss at least the next two weeks.

Richmond now looks ahead to Fremantle in Round 8.