North Melbourne forward Jarrad Waite and Melbourne key tall Jesse Hogan have both been ruled out of their side's clash at Blundstone Arena on Saturday afternoon.

Waite injured his calf and was ruled out during the third quarter, while Hogan suffered a shoulder injury following this incident.

Hogan immediately went down to the rooms following his clash with Luke McDonald, and needed to have his jumper cut off in the rooms due to his shoulder being in so much pain.

Waite has struggled with a calf problem this season, and missed rounds 16-17 with the lower leg issue.

The 34-year-old battled through the second and third quarters with the injury, before being ruled out late in the third quarter.

Both club's will be without their star forwards for the final term.

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