St Kilda have asked former Collingwood defender Jonathon Marsh to come into the club for a medical on Wednesday, in a bid to shore up their defence with their current injury crisis.

According to AFL.com.au, the Saints are looking at Marsh as a replacement to Jake Carlisle, who will be out for most of the season with a back injury.

However, given the Saints are hopeful Carlisie can return by season's end, St Kilda are tipped to put injured draftee Jack Bytel on the long-term injury list, to free up a spot for Marsh.

Marsh can join the Saints under the new pre-season supplemental selection period rule, with the deadline for players joining clubs via the rule coming on Friday, March 15.

Marsh played 15 games for the Magpies across the 2015-16 seasons.