Collingwood's marquee AFLW talent is set to leave the club after their first two seasons together.

Mo Hope will sign with North Melbourne as they look to make a big splash in their first season a part of the AFL women's league. Already signing some big names, North Melbourne seems to be on track to make some noise playing out of Arden street.

Hope signed with Collingwood in 2016 as one of its marquee players for the inaugural AFLW season. The Pies have been disappointing over the past two seasons as they failed to make the grand final twice.

Hope hasn't done much to help as she averaged only seven touches and one goal per game over 13-games. Hope, who is now 30, is yet to reach her potential as one of the league's top superstars.

North Melbourne have been strongly targeting the 30 year old this off-season and now look set to sign her by the day's end, according to AFL.com.au.

Hope will join Emma Kearney (Western Bulldogs), Jasmine Garner (Collingwood), Jess Duffin (Collingwood), Emma King (Collingwood), Jamie Stanton (Brisbane), Tahlia Randall (Brisbane) and Danielle Hardiman (Carlton) in a long list of talented players to be acquired by North Melbourne this off-season.