GWS vice-captain Stephen Coniglio will miss the next 10 weeks of football with an ankle injury he suffered in his side's three-point win over Collingwood on Saturday.

Coniglio sustained a syndesmosis injury during the fourth quarter of the contest, and will now require surgery to repair his ankle.

“It’s always disappointing to lose a player for an extended period of time, but especially one of the calibre of Stephen who’s already had an interrupted start to the season," Giants Head of Athletic Performance David Joyce told the club's website.

“The damage to Stephen’s ankle is significantly worse than the previous injury so he’ll undergo surgery before commencing a thorough rehabilitation program.

“We have no doubt that Stephen will attack his rehabilitation with the same diligence he does all areas of his football and will return to the field in peak condition later in the season.”

Coniglio also missed the first six rounds of the season with an ankle injury.

Aidan Corr and Sam Reid also didn't finish Saturday's game through injuries, as the pair both left the field due to concussion, and will be tested later in the week to determine their availability for this Saturday's clash with Richmond.