Melbourne will make four changes for its crucial clash with Greater Western Sydney on Saturday.

The Dees will welcome back co-captain Nathan Jones from injury and the experienced Bernie Vince from suspension, as they look to sure up their spot inside the top eight following last week's four-point loss to North Melbourne.

Coach Simon Goodwin also revealed on Thursday the Dees will also blood former basketballer, Corey Maynard who will make his debut.

Maynard, the brother of Collingwood's Brayden, joined the club as a category B rookie at the end of last year after playing college basketball in the United States and representing Australia at junior level.

"Corey Maynard will make his AFL debut this weekend. It's very exciting for the club," Goodwin said.

"He has really developed nicely during the year and played some strong VFL footy."

Meanwhile the Demons will include either Sam Weideman or Cam Pedersen to replace the injured Jesse Hogan, who broke his collarbone against the Roos last Saturday.

"We have two players in Cam Pedersen and Sam Weideman who have had great form in the VFL," Goodwin said.

"We'll make our decision on Hogan's replacement later today."

The Giants host the Demons in Canberra at 1.45pm on Saturday afternoon.