GOLD COAST, AUSTRALIA - AUGUST 30: Luke McDonald of the Kangaroos looks dejected during the round 14 AFL match between the Gold Coast Suns and the North Melbourne Kangaroos at Metricon Stadium on August 30, 2020 in Gold Coast, Australia. (Photo by Matt Roberts/AFL Photos/via Getty Images)

Perth's three-day lockdown is set to have large ramifications on the next few weeks for the AFL, with as many as seven clubs already impacted.

On Friday the Western Australian Government confirmed that the Perth and Peel districts would enter a snap lockdown after a resurgence of community transmitted COVID-19 cases.

The lockdown will mean Saturday night's fixture between Fremantle and North Melbourne at Optus Stadium will take place behind closed doors.

The AFL and the Kangaroos are currently working with the Victorian government to allow North Melbourne to return home after their clash against the Dockers and avoid a 14-day quarantine.

MELBOURNE, AUSTRALIA - APRIL 02: The Kangaroos look dejected after a loss during the 2021 AFL Round 03 match between the North Melbourne Kangaroos and the Western Bulldogs at Marvel Stadium on April 02, 2021 in Melbourne, Australia. (Photo by Michael Willson/AFL Photos via Getty Images)

The league will also be in discussions with the Tasmanian Government as the Kangaroos are scheduled to face Melbourne at Blundstone Arena in eight days time.

There is a likely outcome where that game is moved to Marvel Stadium depending on whether or not the Kangaroos are granted an exemption to enter the island state without being required to quarantine.

The West Coast Eagles have already been given the all-clear to face Geelong on Saturday afternoon, with any patrons from red-zone areas of Western Australia told not attend the match at Kardinia Park.

The Eagles faced Collingwood in Round 5 last Thursday, with that encounter now placing Magpies players in isolation and away from training on the eve of their ANZAC Day clash against Essendon.

Collingwood's training was cancelled as players await results of their COVID-19 tests, but Sunday's clash is set to go ahead as planned.

Magpies midfielder Brayden Sier will not feature in Collingwood's VFL side this weekend after he returned from Perth and was listed to face Essendon's reserves at Victoria Park.

Carlton have also been brought into the latest COVID-19 whirlwind, with incoming consultancy coach John Worsfold told to isolate until he receives a negative test.

Worsfold arrived in Victoria from Perth ahead of the Blues' clash with Brisbane on Saturday afternoon at Marvel Stadium.