Williams suffered the injury in the first quarter and was subbed out by quarter time. The ex-Giant underwent scans that revealed a high-grade calf strain and is now expected to be sidelined for 10-12 weeks.
Carlton Head of Football Brad Lloyd stated his disappointment in the star's injury, noting that the squad has been forced to make several rotations since the start of the season due to injury, as well as complementing the team's persistence to persevere through the struggles.
“We took the time to get Zac back to Melbourne and get a scan today to assess the injury fully, which unfortunately has confirmed he will be out of the side for an extended period,” Lloyd said.
“Zac is understandably disappointed given the work he’s done to get himself playing good football and performing an important role as part of our back six.
“We’ve had a number of personnel changes over the opening nine rounds but to the players’ credit they have adapted and there will be another opportunity for someone to step up and take their chance at senior level.”
Williams will join a growing injury list at Princes Park, with Jack Martin (calf), Mitch McGovern (hamstring), Harry McKay (knee), Marc Pittonet (knee) and Liam Stocker (shoulder) also manning the club's casualty ward.