With an extensive injury list heading into Round 1, Ross Lyon and his team will be forced to move the magnets around to fill some spots.
Max King and Tim Membrey both won't feature in Round 1, with King expected to miss at least the opening month of the season, while Jack Hayes and Matthew Allison are also on the injury list, leaving the forward stocks in disarray.
Speaking to media on Monday, Byrnes revealed that untried rookie Anthony Caminiti could find himself as a Round 1 debutant, just a month after joining the club via the Supplemental Selection Period.
"Injuries breed opportunity for some other blokes," Byrnes said.
"Anthony Caminiti has come in, he's new to the club and has been really good so looking forward to seeing what he can do if he gets the call and we've got some others there who have been doing really well as well.
"He's obviously physically pretty gifted, can run and jump and take good marks."
Speaking on exciting young draftee Mattaes Phillipou, Byrnes said that he had definitely put his hand up for selection in the side's season opener after impressive pre-season form.
"He's definitely put his name there," Byrnes said.
"He had a great summer, great pre-season and he's a pretty impressive kid so he has done everything right to get selected.
"He's just the ultimate professional, he can kick the ball very far, he always finds himself in good spots so I think he's a bit flexible, you can play him anywhere really."
St Kilda's mounting injuries were made worse on Monday, with the confirmed news that Seb Ross will also not be available for Round 1, while Nick Coffield will miss between 4-6 weeks after suffering a calf strain.