St Kilda released a statement on Friday afternoon signalling their support of Jones' decision to put his well being first.
Chief Operating Officer Simon Lethlean said that the club would stand by Jones and allow him as much time as he needs.
"Zak Jones has been granted a leave of absence to focus on his personal health and wellbeing," Lethlean said in a statement.
"Zak’s welfare is the number one priority and he will be given as much time as he needs, with the full support of the club.
"On behalf of the Jones family, we request their privacy is respected at this time."
The Saints face a make or break season with their list raising eyebrows after a disappointing 2021. St Kilda missed the finals after making a semi-final the season prior.
With coach Brett Ratten going into the last year of his contract, the pressure could quickly mount at RSEA Park should the Saints get off to a slow start.