Macmillan may not even return to action in 2017, given his finger injury will require at least a six-week recovery period.
North Melbourne doctor Peter Baquie said the defender will need surgery to repair the injury.
“Jamie will require surgery to repair the flexor tendon after it was pulled off the bone,” Baquie told nmfc.com.au.
“A surgeon will reattach the tendon on Thursday and unfortunately, that means Jamie is looking at around six to eight weeks on the sidelines, but we’re very optimistic about it being the former.”
Waite will join Macmillan on the sidelines for at least 3-4 weeks, after sustaining a calf injury in their lost to the Suns on Saturday.
“Depending on his recovery, Jarrad could be looking at about three to four weeks,” Baquie added.
Marley Williams will also miss another 1-2 weeks with a back strain, after being a late withdrawal from the Gold Coast fixture.