Carlton with be down two men on the bench as midfielder Patrick Cripps and defender Simon White have been ruled out for the remainder of the match against Melbourne on Sunday afternoon.

Both players suffered their respective injuries in the second quarter, as Cripps left the field with a lower leg injury, while White received a knock to his knee and limped off late.

Cripps was helped off the field after receiving a boot to the leg, while making an attempt to smother a kick from Jayden Hunt.

White's injury looked a little more innocuous, as the incident looked to be a clash a knees between Jacob Weitering and himself in a marking contest.

The pair were ruled out of the rest of the match during the half-time break, with the Blues leading Melbourne 47-46 at the main change.