Sheppard's 2021 season was cut abruptly short after numerous concussions forced the All-Australian to take some time away.
10 News journalist Lachy Ried is reporting that the 30-year-old will inform teammates of his decision on Monday with the club already knowing of the defenders' intentions.
"Brad Sheppard will announce his retirement next week due to a concussion," Reid tweeted.
Brad Sheppard will announce his retirement next week due to concussion. I’m hearing he’s told Eagles bosses of his decision but he’ll tell his teammates on Monday.
— Lachy Reid (@Lachy_Reid) December 2, 2021
"I’m hearing he’s told Eagles bosses of his decision but he’ll tell his teammates on Monday."
West Coast CEO Trevor Nisbett said recently that the Eagles would work with his health the club's main concern.
"With Bradley, it’s taking a bit of time with his concussion diagnosis,” Nisbett told Sportsday WA.
"He’s been getting all the testing and everything he needs done.
"We’ll continue to monitor Brad as the doctors will. I’ll be talking to Brad on a consistent basis to see where it’s falling."
Fellow Eagle Daniel Venables retired earlier this year with a brutal concussion back in 2019 spelling the end to his promising career.