Melbourne have been heavily impacted by injury in the second half of Monday's Queen's Birthday clash with Collingwood, with a trio of names suffering setbacks.

Debutant Daniel Turner was floored after a heavy collision with Magpie Jamie Elliott in the third term, with the defender subbed out after undergoing a concussion test.

Turner ventured down into his side's rooms with less than 10 minutes remaining before the final break, joining captain Max Gawn in gaining treatment from Melbourne's medical staff.

Gawn had suffered a knock to his knee in the opening half before returning to the field, but a further setback saw the premiership ruckman re-enter the rooms.

After eventually returning to ground level, Gawn was placed under further treatment before being injected back into the match.

Defender Harrison Petty was also sent down to the rooms as Gawn came on, gaining treatment after landing on his back in a marking contest.

The Demons brought small forward Kade Chandler into the game as the medical sub, with Turner's debut ending early.