Brisbane defender Sam Skinner has ruptured his ACL in his right knee and will need surgery.
Skinner suffered the injury in the Lions' NEAFL win over GWS on Saturday, and it's the third time in his career he's sustained the same injury, with the first two injuries on his left knee.
The 20-year-old made his long awaited debut against West Coast in round 19 earlier this season, and kicked two goals in the loss.
Skinner was primed to debut towards the back end of the 2016 season, but was struck down by an ACL injury in the week leading up to his debut game.
Brisbane General Manager of Football Operations David Noble said the club was disappointed Skinner suffered another ACL injury, but said they would be behind him once again on his road to recovery.
"The club is extremely disappointed by another blow to Sam's career after seeing how hard he worked over this last summer to get back and make his debut," Noble told lions.com.au.
"Sam has shown great resilience & strength of character with his previous injuries.
"We will provide every support for him and his family from a medical and wellbeing perspective."
In June, Skinner put pen to paper on a two-year contract extension that will see him remain at the club until at least the end of the 2019 season.