The 26-year-old has played five of the Demons' opening seven games this season and finally looked on course for some consistent football. However, in a cruel blow, Smith looks set to miss eight to ten weeks after undergoing surgery on his ankle.
The former Category B Rookie has had an injury-riddled career, only playing 26 career games and missed out on Melbourne's premiership last season after suffering a hamstring injury in the first week of finals.
Hibberd, who hasn't played since the Grand Final, recently suffered a minor setback in his return from a calf injury and appears to still be a few weeks away from returning to action.
The Blues have also suffered an injury blow with forward-turned-defender Mitch McGovern expected to be out for 10-12 weeks after having surgery on his hamstring.
According to carltonfc.com.au, McGovern re-aggravated a hamstring injury in the past week and the club decided surgery was the best option for his rehabilitation.
The former Crow looked set to have a big year in the Blues' defence after a difficult start to his life as a Blue but the injury appears set to keep McGovern out until late in the season.