Adelaide's midfield stocks have taken a hitĀ ahead of their Round 1 clash with the Giants, with up to four players in a race against the clock to be fit to face GWS.

Brad Crouch (hamstring) and Paul Seedsman (groin) are unlikely to recover in time for the game on March 26 at home, while two All-Australian midfielders will be fighting to overcome their injuries.

Rory Sloane (fractured eye socket) and Scott Thompson (shoulder) will join Crouch and Seedsman on the sidelines for the entire JLT Community Series, as the duo will be managed ahead of the GWS fixture.

Sloane suffered his injury during a match simulation drill in mid-February after copping a knock from forward Josh Jenkins, but the 26-year-old should return to face the Giants, although Thompson will need to do a lot to prove his fitness.

"The expectation is they do everything they can to get themselves right, but a finals berth or a premiership isn't won in round one," Crows forward Josh Jenkins told AFL.com.au.

"But it can be lost if you push yourself and if you miss a lot of time afterwards it can be detrimental."

Crouch seems all but ruled out of Adelaide's opening fixture, as his third hamstring injury in his short career should see him heavily managed before returning to action.