PERTH, AUSTRALIA - JULY 15: Cameron Guthrie and Andrew Mackie of the Cats walk down the race after winning and playing their 100th and 250th games respectively during the round 17 AFL match between the Fremantle Dockers and the Geelong Cats at Domain Stadium on July 15, 2016 in Perth, Australia. (Photo by Paul Kane/Getty Images)

Geelong midfielder Cam Guthrie has been withdrawn from Sunday's match against Fremantle due to a calf injury.

Darcy Lang has come into the 25-man squad, with the final 22 to be determined late on Friday afternoon.

Guthrie injured his calf in the opening JLT Series clash against Hawthorn and did not take part in the final two matches.

Check out all the line-ups for round one here.