The 19-year-old will be the first player from the club’s 2018 national draft class to play at the senior level.
The Eagles selected Cameron as pick No.39 in last year’s NAB AFL Draft.
Cameron will be the fourth debutant for the Eagles this season, revealing he discovered the news during a training session on Monday.
“I didn’t want to approach (Simpson), but he approached me, told me to go back and kick it. I had to do a couple of spins and I shanked the first one, but I went back and kicked my second one and all the boys got around me.
“Then (Simpson) came and told me that I would be playing this Thursday night.”
Cameron, while excited for his debut, hopes he will deal well with the occasion.
“I just want to bring my one wood, which is my pressure, and hopefully everything else will come into play and hopefully the ball will come my way,” Cameron said.
“It will probably take a while to sink in, but it’s just another game.
“I’ve probably been leaning on Liam Ryan and Josh Kennedy (in the build-up). They’ve been saying just embrace it and don’t overthink it.”
The young gun claimed his parents and brother were wrapped with the news of his looming debut.
“Mum wasn’t home, I thought she’d be home, so I had to ring and tell her,” he said.
“I told her I was playing my first game this week and she was pretty stoked. Dad’s up north, so I had to ring him. He’s at work, so he’s going to fly down on Wednesday morning (to attend the game).
“My brother Charlie, he just said don’t take it for granted, embrace the week leading up and just go out and play.”