A list so stacked with talent and a multitude of young Victorians, it's tough to retain all of them.
GWS have been no stranger to that concept over the years, and have had to deal with a range of exits - some of whom have gone on to bigger and better things after seeking greener pastures elsewhere.
Here are the 10 best players that GWS have lost since their introduction into the competition.
The number one draft pick requested a trade from the Giants after his first year at the club in 2014, joining the Bulldogs on a seven-year deal.
The 23-year-old well and truly came of age in the 2016 finals series, in particular the Grand Final. Boyd was instrumental in bringing the Bulldogs their second ever premiership, with a memorable final quarter goal sealing the deal.
Had the Giants - who came agonisingly close to a Grand Final birth - held onto Boyd, then there's a good chance that their fortunes would have been completely different.
Quality ruckmen aren't easy to come by, and GWS undoubtedly would have hoped to have the service of Rory Lobb for a number of years to come.
Unfortunately it wasn't to be, as Lobb requested a trade at the end of the 2018 season and returned to his native Western Australia.
The Giants have the short-term luxury of Shane Mumford making a comeback, but that surely isn't to be for too long, and Lobb's absence is likely to be felt in the coming years.
Originally a GWS academy player, Steele could only manage the 17 games in his two seasons with the Giants, and eventually sought a trade at the end of the 2016 season.
The 23-year-old has shown the Giants what they're missing out on, showing his grunt and pressure within the Saints midfield and amassing impressive numbers as well.
Steele came third in the Trevor Barker voting last year.
By the time Will Hoskin-Elliott had decided to seek a trade to Collingwood, the 25-year-old had already firmly established himself at the Giants, playing 52 games and showing the club what he's capable of.
Fast forward to his time at Collingwood and Hoskin-Elliott has well and truly rubbed it in to Giants fans across the country. The livewire was a focal point in the Magpies forward line last year, kicking 42 goals and being a constant presence as the Pies' soared towards a Grand Final birth.
Similar to Lobb, Wilson was also born and bred in WA and after six seasons at the Giants, the 26-year-old decided a return home was necessary.
Wilson's dash and ball use out of the Giant's defensive 50 was pivotal, and his absence was sorely missed as soon as the trade back to Fremantle was set in stone.
Wilson played 77 games with the Giants and featured heavily in their 2016 and 2017 finals series'.
Bruce had played 14 games for the Giants over the course of two years and had hardly established himself, and so a trade to St Kilda beckoned for the 26-year-old.
Fast forward to 2015 and Bruce had become one of the biggest forward threats in the game. In just his second season at the Saints, Bruce was able to notch up 50 goals, following that up with efforts of 38 and 36 respectively in the coming seasons.
The Giants undoubtedly would have wondered what could've been, and the image of Bruce lining up alongside Jeremy Cameron and co. in the Western Sydney forward line would have been a sore sight for Giants fans.
Smith was yet another victim of the Giants' elite midfield which was stacked with talent. Wanting to predominantly play in the midfield, Smith was left with no choice but to ply his trade in the forward line for the majority of his tenure in Western Sydney.
When Smith could no longer make the best 22 in 2017, it became obvious to Smith that a move was necessary, with Essendon deciding to back in the 26-year-old to thrive in the midfield.
Smith paid the Bombers back in spades, becoming a tackling machine for the Dons over the course of the 2018 season, with his constant pressure acts and in & under work being a massive factor in Essendon's impressive run home in the second half of the season.
His debut year at the Tullamarine culminated in winning the Crichton Medal, Essendon's best and fairest award.
A bitter pill to swallow for the Giants.
The 2017 All-Australian was involved in a highly-publicised trade to Essendon at the end of last year, in a deal that was only made official in the closing minutes of the 2018 trade period.
The Giants have had a star-studded midfield over the years, and losing any player of Shiel's calibre is certainly less than ideal for the clubs premiership prospects.
The 26-year-old played 135 for the Giants from 2012 to 2018.
Now in his sixth season at Collingwood, Taylor Adams has been a mainstay within the Magpies best 22, showing what he would have been capable of producing at the Giants had the 25-year-old decided to stay at GWS.
Predominantly plying his trade in the midfield, Adams has been an impressive addition to the Pies outfit ever since he arrived. The Geelong local amasses large numbers, averaging over 29 disposals in 2017 and over 26 in 2018.
Adams has had an injury-interrupted 2019 campaign so far, but is sure to cause headaches when he returns to the fold.
It's hard to look past anyone other than gun midfielder Adam Treloar to take out the top spot.
Ever since his arrival at the end of 2015, Treloar has been one of Collingwood's most important players.
The 26-year-old's run and carry and explosive impact around the contests has been pivotal in the Magpies resurgence over the last couple of years, and is sure to be one of the Pies' most significant names going forward as they strive to win this years premiership.
Having finished runner-up in the best and fairest in 2015, Treloar had his best season to date when he decided to leave the Giants, leaving a gaping hole in the Giants midfield and making them rue his absence ever since.