Pickett and the Tigers contested the Match Review Officer's charge that was deemed as Careless Conduct, Medium Impact and High Contact.
The Tigers and Picket had hoped to have the level of impact of the charge downgraded from medium impact to low.
"I dropped my level to make it safe because there was a height difference between me (and Moore)," Pickett said told the Tribunal, per AFL.com.au.
With the suspension remaining, Pickett will miss Saturday night's Dreamtime match against the Bombers, where the Tigers will wear an Indigenous jumper designed by the Richmond midfielder.
Meanwhile, Swan youngster James Rowbottom has also lost in his appeal to overturn his one-game suspension.
Rowbottom collected Merrett during a loose ball contest at the SCG, with the front-on collision with the Sydney midfielder leaving the Bombers star on the ground for a number of seconds. (Editor's note: a previous version of this story indicated Merrett was left 'bloodied' by the impact, which is not correct.)
The MRO judged the incident as Careless Conduct, Medium Impact and High Contact, resulting in a one-game suspension.
Rowbottom and the Swans argued that the level of impact should have been lowered from medium to low, while stating the Swan did not intend to bump.