Collingwood president Eddie McGuire has slammed the AFL's isolation hubs idea.

The league is exploring a variety ways to get the season back up and running during the coronavirus pandemic following its shutdown after Round 1.

AFL players were told during a phone conference with AFLPA CEO Paul Marsh on Tuesday that a 'worst case scenario' could see them spend 20 of a possible 21 weeks in isolation hubs, a prospect that several big-name stars have resisted.

Utilising hubs could cost the AFL as much as $200,0000 a day in what shapes as a major financial blow.

Speaking on Nine News on Wednesday, McGuire rubbished the idea as a 'doomsday scenario'.

“There is more chance of me being in the Carlton cheersquad from that happening,” McGuire said.

“I actually feel really angry that so many of the players have been geed up; their partners, already under stress, have been further stressed … That is not only a worst-case scenario, that is a doomsday scenario. Complete rubbish, I would have thought.”

The Magpies president told Footy Classified later that night that the league is more likely to adopt a "fly in, fly out" model if state borders are lifted.

"I'm a little bit disappointed and so are a lot of people in the AFL at the moment," he said.

"That was the worst-case scenario painted to the players last night. There's 40 million reasons why no one wants that to ever happen. It'll cost 40 million dollars on the best day to have the hubs, $2000 a week for 1000 people over 20 weeks.

"The AFL is desperately trying to get the best result they can for everybody and the best result is fly in, fly out.

"It means that you will be able to stay in your own bed, you will go to your own club. In Richmond's case, you would go to Punt Road and then on match day you'll get onto a quarantined bus and then get onto a quarantined plane and you might fly to Perth.

"You'll get off and go to a hotel that's quarantined and you'll play West Coast and you might stay for five days and play Fremantle and then you'll fly home."