MELBOURNE, AUSTRALIA - JULY 18: Jake Carlisle of the Saints looks on during an AFL media opportunity at RSEA Park on July 18, 2018 in Melbourne, Australia. (Photo by Michael Willson/AFL Media/Getty Images)

St Kilda have been dealt a big injury blow on Saturday night, with Jake Carlisle ruled out of their clash with Hawthorn at Etihad Stadium.

Carlisle has been withdrawn from the match, and has been replaced in the side by veteran defender Sam Gilbert.

Hawthorn will enter the clash as named.

Brisbane have made a late change ahead of their clash with the Suns on Saturday night, with ruckman Oscar McInerney being withdrawn from the side.

The Lions have replaced the ruckman with forward Ryan Lester.

Gold Coast will enter the clash as selected.