Port Adelaide's Jack Hombsch will miss this week's clash with Collingwood at the MCG.

The defender experienced tightness in his hamstring during last week's win over Melbourne in the Northern Territory, with scans later revelaing a low grade strain.

He is expected to miss two to three weeks.

“Hombsch will miss a couple of weeks,” Port Adelaide assistant coach Michael Voss said.

“So we’ll have to make a little adjustment there.”

Hombsch's replacement down back will likely be either veteran defender Alipate Carlile or youngster Logan Austin, who is yet to make his debut.

“Carlile is one of the options, Austin is the other,” he said.

“Bobby (Carlile) has had a couple of (SANFL) games under his belt now (following a broken wrist) so he will definitely come into consideration, as will Logan.”

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