Grater Western Sydney has suffered a big blow ahead of this Friday's clash with the Western Bulldogs in Canberra.

Co-captain Phil Davis will miss the match after suffering a hamstring injury at training on Tuesday.

"Phil Davis won't play, he suffered a hamstring injury at training yesterday," coach Leon Cameron said on Wednesday morning.

"It's really, really minor, but you don't want your captain being out for these sorts of games, so that’s really disappointing, but there's an opportunity for another couple of lads to step in."

Davis is expected to return for the round seven clash with St Kilda.

The Dogs defeated the Giants by six points in last year's preliminary final at Spotless Stadium.

The Giants host the Bulldogs at UNSW Canberra Oval on Friday night.